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Retroviral integrase protein and intasome nucleoprotein complex structures
Retroviral replication proceeds through the integration of a DNA copy of the viral RNA genome into the host cellular genome, a process that is mediated by the viral integrase (IN) protein. IN catalyzes two distinct chemical reactions: 3’-processing, whereby the viral DNA is recessed by a di- or trin...
Autores principales: | Grawenhoff, Julia, Engelman, Alan N |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Baishideng Publishing Group Inc
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5329712/ https://www.ncbi.nlm.nih.gov/pubmed/28289517 http://dx.doi.org/10.4331/wjbc.v8.i1.32 |
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