The protective effects of propofol against CoCl(2)-induced HT22 cell hypoxia injury via PP2A/CAMKIIα/nNOS pathway

BACKGROUND: Perioperative cerebral ischemia/hypoxia could induce hippocampal injury and has been reported to induce cognitive impairment. In this study, we used cobalt chloride (CoCl(2)) to build a hypoxia model in mouse hippocampal cell lines. Propofol, a widely used intravenous anesthetic agent, h...

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Detalles Bibliográficos
Autores principales: Lu, Yan, Chen, Wei, Lin, Chen, Wang, Jiaqiang, Zhu, Minmin, Chen, Jiawei, Miao, Changhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5329915/
https://www.ncbi.nlm.nih.gov/pubmed/28241801
http://dx.doi.org/10.1186/s12871-017-0327-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5329915/
https://www.ncbi.nlm.nih.gov/pubmed/28241801
http://dx.doi.org/10.1186/s12871-017-0327-1

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