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Heterogeneity of Toll-like receptor 9 signaling in B cell malignancies and its potential therapeutic application

Toll-like receptor 9 (TLR9) is expressed in a variety of B-cell malignancies and works as a bridge between innate and adaptive immunity. CpG oligodeoxynucleotides (CpG ODNs), TLR9 agonists, are able to induce anticancer immune responses and exert direct effects against cancer cells, serving as cance...

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Detalles Bibliográficos
Autores principales: Bai, Ling, Chen, Wei, Chen, Jingtao, Li, Wei, Zhou, Lei, Niu, Chao, Han, Wei, Cui, Jiuwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5329966/
https://www.ncbi.nlm.nih.gov/pubmed/28241765
http://dx.doi.org/10.1186/s12967-017-1152-5