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Heterogeneity of Toll-like receptor 9 signaling in B cell malignancies and its potential therapeutic application
Toll-like receptor 9 (TLR9) is expressed in a variety of B-cell malignancies and works as a bridge between innate and adaptive immunity. CpG oligodeoxynucleotides (CpG ODNs), TLR9 agonists, are able to induce anticancer immune responses and exert direct effects against cancer cells, serving as cance...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5329966/ https://www.ncbi.nlm.nih.gov/pubmed/28241765 http://dx.doi.org/10.1186/s12967-017-1152-5 |