Cargando…
Enhanced Efficacy of 5-Fluorouracil in Combination with a Dual Histone Deacetylase and Phosphatidylinositide 3-Kinase Inhibitor (CUDC-907) in Colorectal Cancer Cells
BACKGROUND/AIMS: 5-Fluorouracil (5-FU) is widely used in the treatment of patients with colorectal cancer (CRC). However, the efficacy of 5-FU as a single agent is limited, with multiple undesired side effects. Therefore, the aim of the current study was to assess the efficacy of CUDC-907 (a dual in...
Autores principales: | Hamam, Rimi, Ali, Dalia, Vishnubalaji, Radhakrishnan, Alsaaran, Zaid F., Chalisserry, Elna Paul, Alfayez, Musaad, Aldahmash, Abdullah, Alajez, Nehad M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5329975/ https://www.ncbi.nlm.nih.gov/pubmed/28139498 http://dx.doi.org/10.4103/1319-3767.199136 |
Ejemplares similares
-
Romidepsin Promotes Osteogenic and Adipocytic Differentiation of Human Mesenchymal Stem Cells through Inhibition of Histondeacetylase Activity
por: Ali, Dalia, et al.
Publicado: (2018) -
Molecular profiling of ALDH1(+) colorectal cancer stem cells reveals preferential activation of MAPK, FAK, and oxidative stress pro-survival signalling pathways
por: Vishnubalaji, Radhakrishnan, et al.
Publicado: (2018) -
CDH1 and IL1-beta expression dictates FAK and MAPKK-dependent cross-talk between cancer cells and human mesenchymal stem cells
por: Al-toub, Mashael, et al.
Publicado: (2015) -
Circulating microRNAs in breast cancer: novel diagnostic and prognostic biomarkers
por: Hamam, Rimi, et al.
Publicado: (2017) -
Multiple intracellular signaling pathways orchestrate adipocytic differentiation of human bone marrow stromal stem cells
por: Ali, Dalia, et al.
Publicado: (2018)