Pharmacokinetic interactions between glimepiride and rosuvastatin in healthy Korean subjects: does the SLCO1B1 or CYP2C9 genetic polymorphism affect these drug interactions?

To improve cardiovascular outcomes, dyslipidemia in patients with diabetes needs to be treated. Thus, these patients are likely to take glimepiride and rosuvastatin concomitantly. Therefore, this study aimed to evaluate the pharmacokinetic (PK) interactions between these two drugs in healthy males a...

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Detalles Bibliográficos
Autores principales: Kim, Choon Ok, Oh, Eun Sil, Kim, Hohyun, Park, Min Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5330189/
https://www.ncbi.nlm.nih.gov/pubmed/28260863
http://dx.doi.org/10.2147/DDDT.S129586

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5330189/
https://www.ncbi.nlm.nih.gov/pubmed/28260863
http://dx.doi.org/10.2147/DDDT.S129586

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