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Adipose-Derived Circulating miRNAs Regulate Gene Expression in Other Tissues

Adipose tissue is a major site of energy storage and plays a role in regulation of metabolism through release of adipokines. Here we show that mice with a fat-specific knockout of the miRNA-processing enzyme Dicer (ADicerKO), as well as humans with lipodystrophy, have major decreases in circulating...

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Detalles Bibliográficos
Autores principales: Thomou, Thomas, Mori, Marcelo A., Dreyfuss, Jonathan M., Konishi, Masahiro, Sakaguchi, Masaji, Wolfrum, Christian, Rao, Tata Nageswara, Winnay, Jonathon N., Garcia-Martin, Ruben, Grinspoon, Steven K., Gorden, Phillip, Kahn, C. Ronald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5330251/
https://www.ncbi.nlm.nih.gov/pubmed/28199304
http://dx.doi.org/10.1038/nature21365