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Adipose-Derived Circulating miRNAs Regulate Gene Expression in Other Tissues
Adipose tissue is a major site of energy storage and plays a role in regulation of metabolism through release of adipokines. Here we show that mice with a fat-specific knockout of the miRNA-processing enzyme Dicer (ADicerKO), as well as humans with lipodystrophy, have major decreases in circulating...
Autores principales: | Thomou, Thomas, Mori, Marcelo A., Dreyfuss, Jonathan M., Konishi, Masahiro, Sakaguchi, Masaji, Wolfrum, Christian, Rao, Tata Nageswara, Winnay, Jonathon N., Garcia-Martin, Ruben, Grinspoon, Steven K., Gorden, Phillip, Kahn, C. Ronald |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5330251/ https://www.ncbi.nlm.nih.gov/pubmed/28199304 http://dx.doi.org/10.1038/nature21365 |
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