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Targeting histone methylation for colorectal cancer

As a leading cause of cancer deaths worldwide, colorectal cancer (CRC) results from accumulation of both genetic and epigenetic alterations. Disruption of epigenetic regulation in CRC, particularly aberrant histone methylation mediated by histone methyltransferases (HMTs) and demethylases (HDMs), ha...

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Detalles Bibliográficos
Autores principales: Huang, Tao, Lin, Chengyuan, Zhong, Linda L. D., Zhao, Ling, Zhang, Ge, Lu, Aiping, Wu, Jiang, Bian, Zhaoxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5330608/
https://www.ncbi.nlm.nih.gov/pubmed/28286564
http://dx.doi.org/10.1177/1756283X16671287