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Assembling Enzymatic Cascade Pathways inside Virus-Based Nanocages Using Dual-Tasking Nucleic Acid Tags

[Image: see text] The packaging of proteins into discrete compartments is an essential feature for cellular efficiency. Inspired by Nature, we harness virus-like assemblies as artificial nanocompartments for enzyme-catalyzed cascade reactions. Using the negative charges of nucleic acid tags, we deve...

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Detalles Bibliográficos
Autores principales: Brasch, Melanie, Putri, Rindia M., de Ruiter, Mark V., Luque, Daniel, Koay, Melissa. S. T., Castón, José R., Cornelissen, Jeroen J. L. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5330652/
https://www.ncbi.nlm.nih.gov/pubmed/28055188
http://dx.doi.org/10.1021/jacs.6b10948