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A High-Capacity Adenoviral Hybrid Vector System Utilizing the Hyperactive Sleeping Beauty Transposase SB100X for Enhanced Integration

For efficient delivery of required genetic elements we utilized high-capacity adenoviral vectors in the past allowing high transgene capacities of up to 36 kb. Previously we explored the hyperactive Sleeping Beauty (SB) transposase (HSB5) for somatic integration from the high-capacity adenoviral vec...

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Detalles Bibliográficos
Autores principales: Boehme, Philip, Zhang, Wenli, Solanki, Manish, Ehrke-Schulz, Eric, Ehrhardt, Anja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5330939/
https://www.ncbi.nlm.nih.gov/pubmed/27434682
http://dx.doi.org/10.1038/mtna.2016.44