Cargando…

A High-Capacity Adenoviral Hybrid Vector System Utilizing the Hyperactive Sleeping Beauty Transposase SB100X for Enhanced Integration

For efficient delivery of required genetic elements we utilized high-capacity adenoviral vectors in the past allowing high transgene capacities of up to 36 kb. Previously we explored the hyperactive Sleeping Beauty (SB) transposase (HSB5) for somatic integration from the high-capacity adenoviral vec...

Descripción completa

Detalles Bibliográficos
Autores principales:	Boehme, Philip, Zhang, Wenli, Solanki, Manish, Ehrke-Schulz, Eric, Ehrhardt, Anja
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5330939/ https://www.ncbi.nlm.nih.gov/pubmed/27434682 http://dx.doi.org/10.1038/mtna.2016.44

Ejemplares similares

Integration Profile and Safety of an Adenovirus Hybrid-Vector Utilizing Hyperactive Sleeping Beauty Transposase for Somatic Integration
por: Zhang, Wenli, et al.
Publicado: (2013)

Correction: Integration Profile and Safety of an Adenovirus Hybrid-Vector Utilizing Hyperactive Sleeping Beauty Transposase for Somatic Integration
por: Zhang, Wenli, et al.
Publicado: (2020)

Transcriptionally regulated and nontoxic delivery of the hyperactive Sleeping Beauty Transposase
por: Cocchiarella, Fabienne, et al.
Publicado: (2016)

One-Vector System for Multiplexed CRISPR/Cas9 against Hepatitis B Virus cccDNA Utilizing High-Capacity Adenoviral Vectors
por: Schiwon, Maren, et al.
Publicado: (2018)

A hyperactive sleeping beauty transposase enhances transgenesis in zebrafish embryos
por: Newman, Morgan, et al.
Publicado: (2010)

Hybrid Adeno-Associated Viral Vectors Utilizing Transposase-Mediated Somatic Integration for Stable Transgene Expression in Human Cells
por: Zhang, Wenli, et al.
Publicado: (2013)

Expanding the Spectrum of Adenoviral Vectors for Cancer Therapy
por: Gao, Jian, et al.
Publicado: (2020)

Correction: Hybrid Adeno-Associated Viral Vectors Utilizing Transposase-Mediated Somatic Integration for Stable Transgene Expression in Human Cells
por: Zhang, Wenli, et al.
Publicado: (2013)

Correction: Hybrid Adeno-Associated Viral Vectors Utilizing Transposase-Mediated Somatic Integration for Stable Transgene Expression in Human Cells
por: Zhang, Wenli, et al.
Publicado: (2020)

RNA Interference Is Responsible for Reduction of Transgene Expression after Sleeping Beauty Transposase Mediated Somatic Integration
por: Rauschhuber, Christina, et al.
Publicado: (2012)

Correction: Integration Profile and Safety of an Adenovirus Hybrid-Vector Utilizing Hyperactive Sleeping Beauty Transposase for Somatic Integration
Publicado: (2014)

Sleeping Beauty transposase structure allows rational design of hyperactive variants for genetic engineering
por: Voigt, Franka, et al.
Publicado: (2016)

A Broad Range of Dose Optima Achieve High-level, Long-term Gene Expression After Hydrodynamic Delivery of Sleeping Beauty Transposons Using Hyperactive SB100x Transposase
por: Podetz-Pedersen, Kelly M, et al.
Publicado: (2016)

CRISPR/Cas9 delivery with one single adenoviral vector devoid of all viral genes
por: Ehrke-Schulz, Eric, et al.
Publicado: (2017)

Adenoviral Vectors Armed with PAPILLOMAVIRUs Oncogene Specific CRISPR/Cas9 Kill Human-Papillomavirus-Induced Cervical Cancer Cells
por: Ehrke-Schulz, Eric, et al.
Publicado: (2020)

Full-length Dysferlin Transfer by the Hyperactive Sleeping Beauty Transposase Restores Dysferlin-deficient Muscle
por: Escobar, Helena, et al.
Publicado: (2016)

A Novel Adenoviral Hybrid-vector System Carrying a Plasmid Replicon for Safe and Efficient Cell and Gene Therapeutic Applications
por: Voigtlander, Richard, et al.
Publicado: (2013)

A Human In Vitro Model to Study Adenoviral Receptors and Virus Cell Interactions
por: Tsoukas, Raphael L., et al.
Publicado: (2022)

Enhanced Tropism of Species B1 Adenoviral-Based Vectors for Primary Human Airway Epithelial Cells
por: Li, Ni, et al.
Publicado: (2019)

A highly soluble Sleeping Beauty transposase improves control of gene insertion
por: Querques, Irma, et al.
Publicado: (2019)

Engineered Sleeping Beauty transposase redirects transposon integration away from genes
por: Miskey, Csaba, et al.
Publicado: (2022)

Sleeping Beauty Transposon Insertions into Nucleolar DNA by an Engineered Transposase Localized in the Nucleolus
por: Kovač, Adrian, et al.
Publicado: (2023)

Viral Vector-Based Delivery of CRISPR/Cas9 and Donor DNA for Homology-Directed Repair in an In Vitro Model for Canine Hemophilia B
por: Gao, Jian, et al.
Publicado: (2018)

Novel Group C Oncolytic Adenoviruses Carrying a miRNA Inhibitor Demonstrate Enhanced Oncolytic Activity In Vitro and In Vivo
por: Doerner, Johannes, et al.
Publicado: (2022)

Transgene Expression and Transposition Efficiency of Two-Component Sleeping Beauty Transposon Vector Systems Utilizing Plasmid or mRNA Encoding the Transposase
por: Tschorn, Natalie, et al.
Publicado: (2022)

High-Capacity Adenoviral Vectors: Expanding the Scope of Gene Therapy
por: Ricobaraza, Ana, et al.
Publicado: (2020)

Engineered Sleeping Beauty Transposon as Efficient System to Optimize Chimp Adenoviral Production
por: Baldassarri, Samantha, et al.
Publicado: (2022)

Targeted adenoviral vectors
por: Vigne, E, et al.
Publicado: (2001)

Xenogenic Adenoviral Vectors
por: Mittal, Suresh K., et al.
Publicado: (2016)

Xenogenic Adenoviral Vectors
por: Both, Gerald W.
Publicado: (2002)

The Folding of the Specific DNA Recognition Subdomain of the Sleeping Beauty Transposase Is Temperature-Dependent and Is Required for Its Binding to the Transposon DNA
por: Leighton, Gage O., et al.
Publicado: (2014)

ADENOVIRAL VECTORS FOR PROTEIN EXPRESSION
por: Von Seggern, Dan J., et al.
Publicado: (1999)

Construction and application of adenoviral vectors
por: Zhang, Hongbo, et al.
Publicado: (2023)

Editorial: Adenoviral Infection and Immunity, and Adenoviral Vectors for Gene Therapy Applications
por: Zhang, Qiwei, et al.
Publicado: (2022)

A single amino acid switch converts the Sleeping Beauty transposase into an efficient unidirectional excisionase with utility in stem cell reprogramming
por: Kesselring, Lisa, et al.
Publicado: (2020)

Ad 2.0: a novel recombineering platform for high-throughput generation of tailored adenoviruses
por: Mück-Häusl, Martin, et al.
Publicado: (2015)

Comparative analysis of the impact of 40 adenovirus types on dendritic cell activation and CD8(+) T cell proliferation capacity for the identification of favorable immunization vector candidates
por: Wang, Xiaoyan, et al.
Publicado: (2023)

Adenoviral Vectors for Hemophilia Gene Therapy
por: Brunetti-Pierri, N, et al.
Publicado: (2013)

The Role of Chromatin in Adenoviral Vector Function
por: Wong, Carmen M., et al.
Publicado: (2013)

Use of adenoviral vectors as veterinary vaccines
por: Ferreira, T B, et al.
Publicado: (2005)

Cannot write session to /tmp/vufind_sessions/sess_9r5sac73od3obdmbj499t1c5lc