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RNA Primer Extension Hinders DNA Synthesis by Escherichia coli Mutagenic DNA Polymerase IV

In Escherichia coli the highly conserved DNA damage regulated dinB gene encodes DNA Polymerase IV (DinB), an error prone specialized DNA polymerase with a central role in stress-induced mutagenesis. Since DinB is the DNA polymerase with the highest intracellular concentrations upon induction of the...

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Detalles Bibliográficos
Autores principales: Tashjian, Tommy F., Lin, Ida, Belt, Verena, Cafarelli, Tiziana M., Godoy, Veronica G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331060/
https://www.ncbi.nlm.nih.gov/pubmed/28298904
http://dx.doi.org/10.3389/fmicb.2017.00288