PERK activation mitigates tau pathology in vitro and in vivo

The RNA‐like endoplasmic reticulum kinase (PERK) is genetically associated with the tauopathy progressive supranuclear palsy (PSP). To elucidate the functional mechanisms underlying this association, we explored PERK activity in brains of PSP patients and its function in three tauopathy models (cult...

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Detalles Bibliográficos
Autores principales: Bruch, Julius, Xu, Hong, Rösler, Thomas W, De Andrade, Anderson, Kuhn, Peer‐Hendrik, Lichtenthaler, Stefan F, Arzberger, Thomas, Winklhofer, Konstanze F, Müller, Ulrich, Höglinger, Günter U
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331260/
https://www.ncbi.nlm.nih.gov/pubmed/28148553
http://dx.doi.org/10.15252/emmm.201606664

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331260/
https://www.ncbi.nlm.nih.gov/pubmed/28148553
http://dx.doi.org/10.15252/emmm.201606664

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