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Modulation of mTOR signaling as a strategy for the treatment of Pompe disease

Mechanistic target of rapamycin (mTOR) coordinates biosynthetic and catabolic processes in response to multiple extracellular and intracellular signals including growth factors and nutrients. This serine/threonine kinase has long been known as a critical regulator of muscle mass. The recent finding...

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Detalles Bibliográficos
Autores principales: Lim, Jeong‐A, Li, Lishu, Shirihai, Orian S, Trudeau, Kyle M, Puertollano, Rosa, Raben, Nina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331267/
https://www.ncbi.nlm.nih.gov/pubmed/28130275
http://dx.doi.org/10.15252/emmm.201606547