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Proteomic Analysis of HDAC3 Selective Inhibitor in the Regulation of Inflammatory Response of Primary Microglia

HDAC3 has been shown to regulate inflammation. However, the role of HDAC3 in primary microglia is largely unknown. RGFP966 is a newly discovered selective HDAC3 inhibitor. In this study, we used protein mass spectrometry to analyze protein alterations in LPS-treated primary microglia with the applic...

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Detalles Bibliográficos
Autores principales: Xia, Mingxu, Zhao, Qiuchen, Zhang, He, Chen, Yanting, Yuan, Zengqiang, Xu, Yun, Zhang, Meijuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331322/
https://www.ncbi.nlm.nih.gov/pubmed/28293439
http://dx.doi.org/10.1155/2017/6237351