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Polyketide stereocontrol: a study in chemical biology
The biosynthesis of reduced polyketides in bacteria by modular polyketide synthases (PKSs) proceeds with exquisite stereocontrol. As the stereochemistry is intimately linked to the strong bioactivity of these molecules, the origins of stereochemical control are of significant interest in attempts to...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Beilstein-Institut
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331325/ https://www.ncbi.nlm.nih.gov/pubmed/28326145 http://dx.doi.org/10.3762/bjoc.13.39 |