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Ensemble and single-molecule dynamics of IFT dynein in Caenorhabditis elegans cilia

Cytoplasmic dyneins drive microtubule-based, minus-end directed transport in eukaryotic cells. Whereas cytoplasmic dynein 1 has been widely studied, IFT dynein has received far less attention. Here, we use fluorescence microscopy of labelled motors in living Caenorhabditis elegans to investigate IFT...

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Detalles Bibliográficos
Autores principales: Mijalkovic, Jona, Prevo, Bram, Oswald, Felix, Mangeol, Pierre, Peterman, Erwin J. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331336/
https://www.ncbi.nlm.nih.gov/pubmed/28230057
http://dx.doi.org/10.1038/ncomms14591