Efficacy of Urtoxazumab (TMA-15 Humanized Monoclonal Antibody Specific for Shiga Toxin 2) Against Post-Diarrheal Neurological Sequelae Caused by Escherichia coli O157:H7 Infection in the Neonatal Gnotobiotic Piglet Model

Enterohemorrhagic Escherichia coli (EHEC) is the most common cause of hemorrhagic colitis and hemolytic uremic syndrome in human patients, with brain damage and dysfunction the main cause of acute death. We evaluated the efficacy of urtoxazumab (TMA-15, Teijin Pharma Limited), a humanized monoclonal...

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Detalles Bibliográficos
Autores principales: Moxley, Rodney A., Francis, David H., Tamura, Mizuho, Marx, David B., Santiago-Mateo, Kristina, Zhao, Mojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331429/
https://www.ncbi.nlm.nih.gov/pubmed/28134751
http://dx.doi.org/10.3390/toxins9020049

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331429/
https://www.ncbi.nlm.nih.gov/pubmed/28134751
http://dx.doi.org/10.3390/toxins9020049

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