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Hypoallergenic Variant of the Major Egg White Allergen Gal d 1 Produced by Disruption of Cysteine Bridges

Background: Gal d 1 (ovomucoid) is the dominant allergen in the chicken egg white. Hypoallergenic variants of this allergen can be used in immunotherapy as an egg allergy treatment approach. We hypothesised that disruption of two of the nine cysteine-cysteine bridges by site-directed mutagenesis wil...

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Detalles Bibliográficos
Autores principales: Dhanapala, Pathum, Withanage-Dona, Dulashi, Tang, Mimi L. K., Doran, Tim, Suphioglu, Cenk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331602/
https://www.ncbi.nlm.nih.gov/pubmed/28230769
http://dx.doi.org/10.3390/nu9020171