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Hypoallergenic Variant of the Major Egg White Allergen Gal d 1 Produced by Disruption of Cysteine Bridges
Background: Gal d 1 (ovomucoid) is the dominant allergen in the chicken egg white. Hypoallergenic variants of this allergen can be used in immunotherapy as an egg allergy treatment approach. We hypothesised that disruption of two of the nine cysteine-cysteine bridges by site-directed mutagenesis wil...
Autores principales: | Dhanapala, Pathum, Withanage-Dona, Dulashi, Tang, Mimi L. K., Doran, Tim, Suphioglu, Cenk |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331602/ https://www.ncbi.nlm.nih.gov/pubmed/28230769 http://dx.doi.org/10.3390/nu9020171 |
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