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Technical advances in global DNA methylation analysis in human cancers

Prototypical abnormalities of genome-wide DNA methylation constitute the most widely investigated epigenetic mechanism in human cancers. Errors in the cellular machinery to faithfully replicate the global 5-methylcytosine (5mC) patterns, commonly observed during tumorigenesis, give rise to misregula...

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Detalles Bibliográficos
Autores principales: Chowdhury, Basudev, Cho, Il-Hoon, Irudayaraj, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331624/
https://www.ncbi.nlm.nih.gov/pubmed/28261325
http://dx.doi.org/10.1186/s13036-017-0052-9