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Technical advances in global DNA methylation analysis in human cancers

Prototypical abnormalities of genome-wide DNA methylation constitute the most widely investigated epigenetic mechanism in human cancers. Errors in the cellular machinery to faithfully replicate the global 5-methylcytosine (5mC) patterns, commonly observed during tumorigenesis, give rise to misregula...

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Detalles Bibliográficos
Autores principales:	Chowdhury, Basudev, Cho, Il-Hoon, Irudayaraj, Joseph
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331624/ https://www.ncbi.nlm.nih.gov/pubmed/28261325 http://dx.doi.org/10.1186/s13036-017-0052-9

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