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Presence of an interferon signature in individuals who are anti-nuclear antibody positive lacking a systemic autoimmune rheumatic disease diagnosis

BACKGROUND: Elevated levels of type I interferons (IFNs) are a characteristic feature of the systemic autoimmune rheumatic diseases (SARDs) and are thought to play an important pathogenic role. However, it is unknown whether these elevations are seen in anti-nuclear antibody–positive (ANA(+)) indivi...

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Detalles Bibliográficos
Autores principales: Wither, Joan, Johnson, Sindhu R., Liu, Tony, Noamani, Babak, Bonilla, Dennisse, Lisnevskaia, Larissa, Silverman, Earl, Bookman, Arthur, Landolt-Marticorena, Carolina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331647/
https://www.ncbi.nlm.nih.gov/pubmed/28245862
http://dx.doi.org/10.1186/s13075-017-1243-y