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In search of druggable targets for GBM amino acid metabolism

BACKGROUND: Amino acid (AA) pathways may contain druggable targets for glioblastoma (GBM). Literature reviews and GBM database (http://r2.amc.nl) analyses were carried out to screen for such targets among 95 AA related enzymes. METHODS: First, we identified the genes that were differentially express...

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Detalles Bibliográficos
Autores principales: Panosyan, Eduard H., Lin, Henry J., Koster, Jan, Lasky, Joseph L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331648/
https://www.ncbi.nlm.nih.gov/pubmed/28245795
http://dx.doi.org/10.1186/s12885-017-3148-1