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Regulation of stem-like cancer cells by glutamine through β-catenin pathway mediated by redox signaling
BACKGROUND: Cancer stem cells (CSCs) are thought to play an important role in tumor recurrence and drug resistance, and present a major challenge in cancer therapy. The tumor microenvironment such as growth factors, nutrients and oxygen affect CSC generation and proliferation by providing the necess...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331650/ https://www.ncbi.nlm.nih.gov/pubmed/28245869 http://dx.doi.org/10.1186/s12943-017-0623-x |