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Mechanisms of Groucho-mediated repression revealed by genome-wide analysis of Groucho binding and activity

BACKGROUND: The transcriptional corepressor Groucho (Gro) is required for the function of many developmentally regulated DNA binding repressors, thus helping to define the gene expression profile of each cell during development. The ability of Gro to repress transcription at a distance together with...

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Detalles Bibliográficos
Autores principales: Chambers, Michael, Turki-Judeh, Wiam, Kim, Min Woo, Chen, Kenny, Gallaher, Sean D., Courey, Albert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331681/
https://www.ncbi.nlm.nih.gov/pubmed/28245789
http://dx.doi.org/10.1186/s12864-017-3589-6