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Indirect tolerability comparison of Deutetrabenazine and Tetrabenazine for Huntington disease

BACKGROUND: Vesicular monoamine transporter 2 (VMAT2) inhibitors can improve hyperkinetic movements, and are effective treatment options for chorea of Huntington disease (HD). Tetrabenazine was assessed for treating chorea in the TETRA-HD trial, and while efficacious, there are tolerability concerns...

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Detalles Bibliográficos
Autores principales: Claassen, Daniel O., Carroll, Benjamin, De Boer, Lisa M., Wu, Eric, Ayyagari, Rajeev, Gandhi, Sanjay, Stamler, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331691/
https://www.ncbi.nlm.nih.gov/pubmed/28265459
http://dx.doi.org/10.1186/s40734-017-0051-5