Spectrum of somatic mutations detected by targeted next-generation sequencing and their prognostic significance in adult patients with acute lymphoblastic leukemia

Target-specific next-generation sequencing technology was used to analyze 112 genes in adult patients with acute lymphoblastic leukemia (ALL). This sequencing mainly focused on the specific mutational hotspots. Among the 121 patients, 93 patients were B-ALL (76.9%), and 28 patients (23.1%) were T-AL...

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Detalles Bibliográficos
Autores principales: Feng, Juan, Li, Yan, Jia, Yujiao, Fang, Qiuyun, Gong, Xiaoyuan, Dong, Xiaobao, Ru, Kun, Li, Qinghua, Zhao, Xingli, Liu, Kaiqi, Wang, Min, Tian, Zheng, Jia, Yannan, Wang, Ying, Lin, Dong, Wei, Hui, Tang, Kejing, Mi, Yingchang, Wang, Jianxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331692/
https://www.ncbi.nlm.nih.gov/pubmed/28245838
http://dx.doi.org/10.1186/s13045-017-0431-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331692/
https://www.ncbi.nlm.nih.gov/pubmed/28245838
http://dx.doi.org/10.1186/s13045-017-0431-1

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