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Cytosolic thioredoxin reductase 1 is required for correct disulfide formation in the ER
Folding of proteins entering the secretory pathway in mammalian cells frequently requires the insertion of disulfide bonds. Disulfide insertion can result in covalent linkages found in the native structure as well as those that are not, so‐called non‐native disulfides. The pathways for disulfide for...
Autores principales: | Poet, Greg J, Oka, Ojore BV, van Lith, Marcel, Cao, Zhenbo, Robinson, Philip J, Pringle, Marie Anne, Arnér, Elias SJ, Bulleid, Neil J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331760/ https://www.ncbi.nlm.nih.gov/pubmed/28093500 http://dx.doi.org/10.15252/embj.201695336 |
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