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Endoplasmic Reticulum Stress Regulates Hepatic Bile Acid Metabolism in Mice

BACKGROUND & AIMS: Cholestasis promotes endoplasmic reticulum (ER) stress in the liver, however, the effect of ER stress on hepatic bile acid metabolism is unknown. We aim to determine the effect of ER stress on hepatic bile acid synthesis and transport in mice. METHODS: ER stress was induced ph...

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Detalles Bibliográficos
Autores principales: Henkel, Anne S., LeCuyer, Brian, Olivares, Shantel, Green, Richard M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331781/
https://www.ncbi.nlm.nih.gov/pubmed/28275692
http://dx.doi.org/10.1016/j.jcmgh.2016.11.006