Cargando…

Hyaluronidase 2 Deficiency Causes Increased Mesenchymal Cells, Congenital Heart Defects, and Heart Failure

BACKGROUND—: Hyaluronan (HA) is required for endothelial-to-mesenchymal transition and normal heart development in the mouse. Heart abnormalities in hyaluronidase 2 (HYAL2)–deficient (Hyal2(−)(/−)) mice and humans suggested removal of HA is also important for normal heart development. We have perfor...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chowdhury, Biswajit, Xiang, Bo, Liu, Michelle, Hemming, Richard, Dolinsky, Vernon W., Triggs-Raine, Barbara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2017
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331876/ https://www.ncbi.nlm.nih.gov/pubmed/28196902 http://dx.doi.org/10.1161/CIRCGENETICS.116.001598

Ejemplares similares

Mutations in HYAL2, Encoding Hyaluronidase 2, Cause a Syndrome of Orofacial Clefting and Cor Triatriatum Sinister in Humans and Mice
por: Muggenthaler, Martina M. A., et al.
Publicado: (2017)

Mutation of EMG1 causing Bowen–Conradi syndrome results in reduced cell proliferation rates concomitant with G2/M arrest and 18S rRNA processing delay
por: Armistead, Joy, et al.
Publicado: (2014)

Preeclampsia and Fetal Congenital Heart Defects
por: Ferreira, Bárbara D., et al.
Publicado: (2022)

Surgery for Congenital Heart Defects
por: Singleton, Matthew J.
Publicado: (2008)

Folate Deficiency and Folic Acid Supplementation: The Prevention of Neural-Tube Defects and Congenital Heart Defects
por: Czeizel, Andrew E., et al.
Publicado: (2013)

Vulnerability of the Developing Heart to Oxygen Deprivation as a Cause of Congenital Heart Defects
por: Kenchegowda, Doreswamy, et al.
Publicado: (2014)

Mutations in Hnrnpa1 cause congenital heart defects
por: Yu, Zhe, et al.
Publicado: (2018)

Congenital heart defects in genetics syndromes
por: Digilio, M Cristina, et al.
Publicado: (2015)

Ventricular Function in Congenital Heart Defects
por: Corno, Antonio F.
Publicado: (2016)

Polymalformative syndrome with congenital heart defect
por: Marcos, Sara Pimentel, et al.
Publicado: (2015)

Pregestational Diabetes and Congenital Heart Defects
por: Maduro, Catarina, et al.
Publicado: (2022)

Experimental Studies of the Molecular Pathways Regulated by Exercise and Resveratrol in Heart, Skeletal Muscle and the Vasculature
por: Dolinsky, Vernon W., et al.
Publicado: (2014)

Quality of Life After Heart Transplantation for Congenital Heart Defect
por: Martens, Sabrina, et al.
Publicado: (2022)

The role of iron deficiency in heart failure
por: Caminiti, Giuseppe, et al.
Publicado: (2023)

Arrhythmias in adults with congenital heart disease and heart failure
por: Bessière, Francis, et al.
Publicado: (2021)

Editorial: Heart Failure in Pediatrics and Congenital Heart Disease
por: Azeka, Estela, et al.
Publicado: (2022)

Maternal Genome-Wide DNA Methylation Patterns and Congenital Heart Defects
por: Chowdhury, Shimul, et al.
Publicado: (2011)

The Cardiac Neural Crest Cells in Heart Development and Congenital Heart Defects
por: Erhardt, Shannon, et al.
Publicado: (2021)

Acute Severe Heart Failure in a Child With Congenital Heart Defect and Multisystem Inflammatory Syndrome in Children (MIS-C)
por: Pawar, Ravindra S., et al.
Publicado: (2021)

Risk factors predisposing to congenital heart defects
por: Ul Haq, Faheem, et al.
Publicado: (2011)

New insights in genetics of congenital heart defects
por: Digilio, MC
Publicado: (2002)

Three dimensional echocardiography in congenital heart defects
por: Shirali, Girish S.
Publicado: (2008)

Evaluation of Swallowing in Infants with Congenital Heart Defect
por: Pereira, Karine da Rosa, et al.
Publicado: (2014)

What Is New in Genetics of Congenital Heart Defects?
por: Digilio, Maria Cristina, et al.
Publicado: (2016)

Why are congenital heart defects being missed?
por: van Nisselrooij, A. E. L., et al.
Publicado: (2020)

Prenatal diagnosis of congenital heart defects: echocardiography
por: Sun, Heather Y.
Publicado: (2021)

Cutaneous eruption in neonate with congenital heart defect
por: Raman, Justin, et al.
Publicado: (2022)

Angiopoietin-2 in Adults with Congenital Heart Disease and Heart Failure
por: Lukasz, Alexander, et al.
Publicado: (2013)

Iron deficiency in heart failure
por: Loncar, Goran, et al.
Publicado: (2021)

Creatine deficiency and heart failure
por: Del Franco, Annamaria, et al.
Publicado: (2021)

Acquired Comorbidities in Adults with Congenital Heart Disease: An Analysis of the German National Register for Congenital Heart Defects
por: Maurer, Susanne J., et al.
Publicado: (2021)

Tropomyosin 1: Multiple roles in the developing heart and in the formation of congenital heart defects
por: England, Jennifer, et al.
Publicado: (2017)

Corience: A website dedicated to congenital heart defects
por: Specht, K
Publicado: (2010)

Tessier Number 30 Clefts With Congenital Heart Defects
por: Tafreshi, Mona, et al.
Publicado: (2015)

Current diagnosis and treatments for critical congenital heart defects
por: ZENG, ZHANDONG, et al.
Publicado: (2016)

Congenital Heart Defects and Ciliopathies Associated With Renal Phenotypes
por: Gabriel, George C., et al.
Publicado: (2018)

Geographical distribution of congenital heart defects in Saudi Arabia
por: Greer, W., et al.
Publicado: (2005)

Ethnic and socioeconomic variation in incidence of congenital heart defects
por: Knowles, Rachel L, et al.
Publicado: (2017)

Fast tracking after repair of congenital heart defects
por: Garg, Rajnish Kumar, et al.
Publicado: (2020)

Maternal occupational exposure and congenital heart defects in offspring
por: Spinder, Nynke, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_ognt1bjsh5pt5ket52t0h73bj5