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Guanylate binding protein 5: Impairing virion infectivity by targeting retroviral envelope glycoproteins

Guanylate binding proteins (GBPs) are interferon-inducible cellular factors that belong to the superfamily of guanosine triphosphatases (GTPases) and play important roles in the cell-intrinsic defense against bacteria, protozoa and viruses. In a recent report in Cell Host & Microbe, we identify...

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Detalles Bibliográficos
Autores principales: Hotter, Dominik, Sauter, Daniel, Kirchhoff, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331900/
https://www.ncbi.nlm.nih.gov/pubmed/27275775
http://dx.doi.org/10.1080/21541248.2016.1189990