RNAi screens for Rho GTPase regulators of cell shape and YAP/TAZ localisation in triple negative breast cancer

In order to metastasise, triple negative breast cancer (TNBC) must make dynamic changes in cell shape. The shape of all eukaryotic cells is regulated by Rho Guanine Nucleotide Exchange Factors (RhoGEFs), which activate Rho-family GTPases in response to mechanical and informational cues. In contrast,...

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Detalles Bibliográficos
Autores principales: Pascual-Vargas, Patricia, Cooper, Samuel, Sero, Julia, Bousgouni, Vicky, Arias-Garcia, Mar, Bakal, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Data Descriptor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5332010/
https://www.ncbi.nlm.nih.gov/pubmed/28248929
http://dx.doi.org/10.1038/sdata.2017.18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5332010/
https://www.ncbi.nlm.nih.gov/pubmed/28248929
http://dx.doi.org/10.1038/sdata.2017.18

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