Genome-wide siRNA screen of genes regulating the LPS-induced NF-κB and TNF-α responses in mouse macrophages

The mammalian innate immune system senses many bacterial stimuli through the toll-like receptor (TLR) family. Activation of the TLR4 receptor by bacterial lipopolysaccharide (LPS) is the most widely studied TLR pathway due to its central role in host responses to gram-negative bacterial infection an...

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Detalles Bibliográficos
Autores principales: Li, Ning, Katz, Samuel, Dutta, Bhaskar, Benet, Zachary L., Sun, Jing, Fraser, Iain D.C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Data Descriptor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5332015/
https://www.ncbi.nlm.nih.gov/pubmed/28248925
http://dx.doi.org/10.1038/sdata.2017.8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5332015/
https://www.ncbi.nlm.nih.gov/pubmed/28248925
http://dx.doi.org/10.1038/sdata.2017.8

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