Safety evaluation of a vaccine: Effect in maternal reproductive outcome and fetal anomaly frequency in rats using a leishmanial vaccine as a model

While the immunogenic potential of the vaccination against infectious diseases was extensively shown, data on the safety assessment of recombinant proteins in vaccine formulations administered during pregnancy are still scarce. In the current study, the antigenicity of a vaccine against leishmaniasi...

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Detalles Bibliográficos
Autores principales: Moraes-Souza, Rafaianne Q., Reinaque, Ana Paula, Soares, Thaigra S., Silva, Ana Luiza T., Giunchetti, Rodolfo C., Takano, Maria A. S., Akamatsu, Milena A., Kubrusly, Flávia S., Lúcio-Macarini, Fernanda, Raw, Isaias, Iourtov, Dmitri, Ho, Paulo Lee, Bueno, Lilian L., Fujiwara, Ricardo T., Volpato, Gustavo T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5332059/
https://www.ncbi.nlm.nih.gov/pubmed/28249007
http://dx.doi.org/10.1371/journal.pone.0172525

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5332059/
https://www.ncbi.nlm.nih.gov/pubmed/28249007
http://dx.doi.org/10.1371/journal.pone.0172525

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