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HLA specificities are associated with prognosis in IGHV-mutated CLL-like high-count monoclonal B cell lymphocytosis

INTRODUCTION: Molecular alterations leading progression of asymptomatic CLL-like high-count monoclonal B lymphocytosis (hiMBL) to chronic lymphocytic leukemia (CLL) remain poorly understood. Recently, genome-wide association studies have found 6p21.3, where the human leukocyte antigen (HLA) system i...

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Detalles Bibliográficos
Autores principales: García-Álvarez, María, Alcoceba, Miguel, López-Parra, Miriam, Puig, Noemí, Antón, Alicia, Balanzategui, Ana, Prieto-Conde, Isabel, Jiménez, Cristina, Sarasquete, María E., Chillón, M. Carmen, Gutiérrez, María Laura, Corral, Rocío, Alonso, José María, Queizán, José Antonio, Vidán, Julia, Pardal, Emilia, Peñarrubia, María Jesús, Bastida, José M., García-Sanz, Ramón, Marín, Luis, González, Marcos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5332061/
https://www.ncbi.nlm.nih.gov/pubmed/28249016
http://dx.doi.org/10.1371/journal.pone.0172978