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Effects of sevuparin on rosette formation and cytoadherence of Plasmodium falciparum infected erythrocytes
In severe falciparum malaria cytoadherence of parasitised red blood cells (PRBCs) to vascular endothelium (causing sequestration) and to uninfected red cells (causing rosette formation) contribute to microcirculatory flow obstruction in vital organs. Heparin can reverse the underlying ligand-recepto...
Autores principales: | , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5332063/ https://www.ncbi.nlm.nih.gov/pubmed/28249043 http://dx.doi.org/10.1371/journal.pone.0172718 |