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A Randomized Controlled Trial of the Effects of Febuxostat Therapy on Adipokines and Markers of Kidney Fibrosis in Asymptomatic Hyperuricemic Patients With Diabetic Nephropathy

BACKGROUND: In observational studies, higher uric acid levels are associated with metabolic syndrome, diabetes, and kidney disease. OBJECTIVE: The objective of this study is to examine whether reduction of plasma uric acid with febuxostat, a xanthine oxido reductase inhibitor, impacts adipose tissue...

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Detalles Bibliográficos
Autores principales: Beddhu, Srinivasan, Filipowicz, Rebecca, Wang, Bin, Wei, Guo, Chen, Xiaorui, Roy, Abinash C., DuVall, Scott L., Farrukh, Hanadi, Habib, Arsalan N., Bjordahl, Terrence, Simmons, Debra L., Munger, Mark, Stoddard, Greg, Kohan, Donald E., Greene, Tom, Huang, Yufeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5332087/
https://www.ncbi.nlm.nih.gov/pubmed/28270924
http://dx.doi.org/10.1177/2054358116675343