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An aging-independent replicative lifespan in a symmetrically dividing eukaryote

The replicative lifespan (RLS) of a cell—defined as the number of cell divisions before death—has informed our understanding of the mechanisms of cellular aging. However, little is known about aging and longevity in symmetrically dividing eukaryotic cells because most prior studies have used budding...

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Detalles Bibliográficos
Autores principales: Spivey, Eric C, Jones, Stephen K, Rybarski, James R, Saifuddin, Fatema A, Finkelstein, Ilya J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5332158/
https://www.ncbi.nlm.nih.gov/pubmed/28139976
http://dx.doi.org/10.7554/eLife.20340