An Integrated Experimental Design for the Assessment of Multiple Toxicological End Points in Rat Bioassays

BACKGROUND: For nearly five decades long-term studies in rodents have been the accepted benchmark for assessing chronic long-term toxic effects, particularly carcinogenicity, of chemicals. The European Food Safety Authority (EFSA) and the World Health Organization (WHO) have pointed out that the cur...

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Detalles Bibliográficos
Autores principales: Manservisi, Fabiana, Marquillas, Clara Babot, Buscaroli, Annalisa, Huff, James, Lauriola, Michelina, Mandrioli, Daniele, Manservigi, Marco, Panzacchi, Simona, Silbergeld, Ellen K., Belpoggi, Fiorella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2016
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5332192/
https://www.ncbi.nlm.nih.gov/pubmed/27448388
http://dx.doi.org/10.1289/EHP419

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5332192/
https://www.ncbi.nlm.nih.gov/pubmed/27448388
http://dx.doi.org/10.1289/EHP419

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