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Genistein suppresses the proliferation of telomerase‐negative cells

In both tumor and yeast cells that lack telomerase, telomeres are maintained via an alternative recombination mechanism. In this study, we tested genistein, a potential TOP2 inhibitor required for telomere–telomere recombination, on the repression of telomere–telomere recombination. Genistein on the...

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Detalles Bibliográficos
Autores principales: Lin, Chuan‐Chuan, Hsieh, Meng‐Hsun, Teng, Shu‐Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5332266/
https://www.ncbi.nlm.nih.gov/pubmed/28265354
http://dx.doi.org/10.1002/fsn3.382