Cargando…

Genistein suppresses the proliferation of telomerase‐negative cells

In both tumor and yeast cells that lack telomerase, telomeres are maintained via an alternative recombination mechanism. In this study, we tested genistein, a potential TOP2 inhibitor required for telomere–telomere recombination, on the repression of telomere–telomere recombination. Genistein on the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lin, Chuan‐Chuan, Hsieh, Meng‐Hsun, Teng, Shu‐Chun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5332266/ https://www.ncbi.nlm.nih.gov/pubmed/28265354 http://dx.doi.org/10.1002/fsn3.382

Ejemplares similares

Genistein suppresses leptin‐induced proliferation and migration of vascular smooth muscle cells and neointima formation
por: Tsai, Yung‐Chieh, et al.
Publicado: (2016)

Cell Proliferation in the Presence of Telomerase
por: Blagoev, Krastan B.
Publicado: (2009)

Telomerase Mediates Lymphocyte Proliferation but Not the Atherosclerosis-Suppressive Potential of Regulatory T-Cells
por: Richardson, Gavin David, et al.
Publicado: (2018)

PARP1 controls KLF4-mediated telomerase expression in stem cells and cancer cells
por: Hsieh, Meng-Hsun, et al.
Publicado: (2017)

Suppression of lymphoma growth by the xenoestrogens bisphenol A and genistein
por: Yakimchuk, Konstantin, et al.
Publicado: (2018)

Genistein Induces Apoptosis and Inhibits Proliferation of HT29 Colon Cancer Cells
por: Shafiee, Gholamreza, et al.
Publicado: (2016)

Human T Cell Differentiation Negatively Regulates Telomerase Expression Resulting in Reduced Activation-Induced Proliferation and Survival
por: Patrick, Michael S., et al.
Publicado: (2019)

Troglitazone suppresses telomerase activity independently of PPARγ in estrogen-receptor negative breast cancer cells
por: Rashid-Kolvear, Fariborz, et al.
Publicado: (2010)

Effect of Genistein on Apoptosis and Proliferation of Hepatocellular Carcinoma Hepa1-6 Cell Line
por: Sanaei, Masumeh, et al.
Publicado: (2018)

Imatinib mesylate (Gleevec) downregulates telomerase activity and inhibits proliferation in telomerase-expressing cell lines
por: Uziel, O, et al.
Publicado: (2005)

Genistein suppresses aerobic glycolysis and induces hepatocellular carcinoma cell death
por: Li, Sainan, et al.
Publicado: (2017)

Telomerase Inhibition by Everolimus Suppresses Smooth Muscle Cell Proliferation and Neointima Formation Through Epigenetic Gene Silencing
por: Aono, Jun, et al.
Publicado: (2016)

Telomerase RNA TERC and the PI3K-AKT pathway form a positive feedback loop to regulate cell proliferation independent of telomerase activity
por: Wu, Shu, et al.
Publicado: (2022)

Semaphorin 5A suppresses the proliferation and migration of lung adenocarcinoma cells
por: Ko, Pin-Hao, et al.
Publicado: (2019)

Genistein inhibits proliferation of colon cancer cells by attenuating a negative effect of epidermal growth factor on tumor suppressor FOXO3 activity
por: Qi, Wentao, et al.
Publicado: (2011)

Isoflavones, Genistein and Daidzein, Regulate Mucosal Immune Response by Suppressing Dendritic Cell Function
por: Wei, John, et al.
Publicado: (2012)

Genistein suppresses FLT4 and inhibits human colorectal cancer metastasis
por: Xiao, Xiao, et al.
Publicado: (2014)

PinX1 suppresses tumorigenesis by negatively regulating telomerase/telomeres in colorectal carcinoma cells and is a promising molecular marker for patient prognosis
por: Qian, Dong, et al.
Publicado: (2016)

Neonatal genistein exposure disrupts ovarian and uterine development in the mouse by inhibiting cellular proliferation
por: WU, Guoyun, et al.
Publicado: (2018)

Cell proliferation and apoptosis in rat mammary glands following combinational exposure to bisphenol A and genistein
por: Wang, Jun, et al.
Publicado: (2014)

Inhibitory Effects of Genistein on Vascular Smooth Muscle Cell Proliferation Induced by Ox-LDL: Role of BKCa Channels
por: Bai, Bing, et al.
Publicado: (2020)

P22. Immunomodulation induced by resveratrol or genistein on proliferation and apoptosis of tumour colon cells
por: Brasoveanu, L, et al.
Publicado: (2014)

Constitutive Expression of Human Telomerase Enhances the Proliferation Potential of Human Mesenchymal Stem Cells
por: Bischoff, David S., et al.
Publicado: (2012)

Genistein modulates the estrogen receptor and suppresses angiogenesis and inflammation in the murine model of peritoneal endometriosis
por: Sutrisno, Sutrisno, et al.
Publicado: (2017)

Genistein Improves the Major Depression through Suppressing the Expression of miR-221/222 by Targeting Connexin 43
por: Shen, Fang, et al.
Publicado: (2018)

Genistein suppresses the mitochondrial apoptotic pathway in hippocampal neurons in rats with Alzheimer's disease
por: Wang, Yan, et al.
Publicado: (2016)

Inhibition of Cell Proliferation and MAP Kinase and Akt Pathways in Oral Squamous cell Carcinoma by Genistein and Biochanin A
por: Johnson, Tara L., et al.
Publicado: (2010)

HnRNP F/H associate with hTERC and telomerase holoenzyme to modulate telomerase function and promote cell proliferation
por: Xu, Chenzhong, et al.
Publicado: (2019)

Targeting EMP3 suppresses proliferation and invasion of hepatocellular carcinoma cells through inactivation of PI3K/Akt pathway
por: Hsieh, Yi-Hsien, et al.
Publicado: (2015)

Inhibition of esophageal-carcinoma cell proliferation by genistein via suppression of JAK1/2-STAT3 and AKT/MDM2/p53 signaling pathways
por: Gao, Jing, et al.
Publicado: (2020)

Genistein Prevents BRCA1 CpG Methylation and Proliferation in Human Breast Cancer Cells with Activated Aromatic Hydrocarbon Receptor
por: Romagnolo, Donato F, et al.
Publicado: (2017)

A comparative study of the effects of genistein and 2-methoxyestradiol on the proteolytic balance and tumour cell proliferation
por: Fajardo, I, et al.
Publicado: (1999)

Nuclear envelope tethering inhibits the formation of ALT-associated PML bodies in ALT cells
por: Yang, Chia-Wei, et al.
Publicado: (2021)

Drug–target–disease network analysis of gene–phenotype connectivity for genistein in ovarian cancer
por: Zhang, Chen, et al.
Publicado: (2018)

Genistein inhibits tumor invasion by suppressing multiple signal transduction pathways in human hepatocellular carcinoma cells
por: Wang, Shulhn-Der, et al.
Publicado: (2014)

Correction to: HnRNP F/H associate with hTERC and telomerase holoenzyme to modulate telomerase function and promote cell proliferation
por: Xu, Chenzhong, et al.
Publicado: (2021)

Genistein Suppresses Prostate Cancer Growth through Inhibition of Oncogenic MicroRNA-151
por: Chiyomaru, Takeshi, et al.
Publicado: (2012)

Novel substituted methylenedioxy lignan suppresses proliferation of cancer cells by inhibiting telomerase and activation of c-myc and caspases leading to apoptosis
por: Giridharan, P, et al.
Publicado: (2002)

SMN and coilin negatively regulate dyskerin association with telomerase RNA
por: Poole, Aaron R., et al.
Publicado: (2016)

Pharmacokinetics Interaction between Imatinib and Genistein in Rats
por: Wang, Zhe, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_qicro5tcqtmslt7iguvlp1bhva