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TRIM8 regulates stemness in glioblastoma through PIAS3‐STAT3

Glioblastoma (GBM) is the most malignant form of primary brain tumor, and GBM stem‐like cells (GSCs) contribute to the rapid growth, therapeutic resistance, and clinical recurrence of these fatal tumors. STAT3 signaling supports the maintenance and proliferation of GSCs, yet regulatory mechanisms ar...

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Detalles Bibliográficos
Autores principales: Zhang, Changming, Mukherjee, Subhas, Tucker‐Burden, Carol, Ross, James L., Chau, Monica J., Kong, Jun, Brat, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5332279/
https://www.ncbi.nlm.nih.gov/pubmed/28100038
http://dx.doi.org/10.1002/1878-0261.12034