DOCK2 Interacts with FLT3 and Modulates the Survival of FLT3-Expressing Leukemia Cells

The FMS-like tyrosine kinase-3 (FLT3) gene is the most commonly mutated gene in acute myeloid leukemia (AML), and patients carrying internal tandem duplication (ITD) mutations have a poor prognosis. Long-term inhibition of FLT3 activity in these patients has been elusive. To provide a more complete...

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Detalles Bibliográficos
Autores principales: Wu, Min, Hamaker, Max, Li, Li, Small, Donald, Duffield, Amy S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5332301/
https://www.ncbi.nlm.nih.gov/pubmed/27748370
http://dx.doi.org/10.1038/leu.2016.284

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5332301/
https://www.ncbi.nlm.nih.gov/pubmed/27748370
http://dx.doi.org/10.1038/leu.2016.284

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