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Stimulation of β-adrenergic receptors plays a protective role via increased expression of RAF-1 and PDX-1 in hyperglycemic rat pancreatic islet (RIN-m5F) cells

INTRODUCTION: It is a widely held view that a progressive reduction of beta-cell mass occurs in the progression of diabetes. RAF-1 kinase and pancreas duodenal homeobox 1 (PDX-1) are major factors that promote survival of cells and maintain normal insulin functions. In this study we investigated the...

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Detalles Bibliográficos
Autores principales: Safi, Sher Zaman, Qvist, Rajes, Ong, Gracie, Karimian, Hamed, Imran, Muhammad, Shah, Ikram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5332455/
https://www.ncbi.nlm.nih.gov/pubmed/28261303
http://dx.doi.org/10.5114/aoms.2016.64131