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Effect of irradiation on DNA synthesis, NBN gene expression and chromosomal stability in cells with NBN mutations

INTRODUCTION: The NBN gene product is part of the MRE11/RAD50/NBN complex, which plays an essential role in genomic stability. In the study we try to answer the question what is the effect of irradiation on DNA synthesis, NBN gene expression and chromosomal stability in cells with homozygous c.657-6...

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Detalles Bibliográficos
Autores principales: Nowak, Jerzy, Świątek-Kościelna, Bogna, Kałużna, Ewelina M., Rembowska, Jolanta, Dzikiewicz-Krawczyk, Agnieszka, Zawada, Mariola, Januszkiewicz-Lewandowska, Danuta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5332466/
https://www.ncbi.nlm.nih.gov/pubmed/28261280
http://dx.doi.org/10.5114/aoms.2017.65452