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Transglutaminase 2 in cartilage homoeostasis: novel links with inflammatory osteoarthritis
Transglutaminase 2 (TG2) is highly expressed during chondrocyte maturation and contributes to the formation of a mineralised scaffold by introducing crosslinks between extracellular matrix (ECM) proteins. In healthy cartilage, TG2 stabilises integrity of ECM and likely influences cartilage stiffness...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Springer Vienna
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5332500/ https://www.ncbi.nlm.nih.gov/pubmed/27510997 http://dx.doi.org/10.1007/s00726-016-2305-1 |