Melatonin Inhibits Glioblastoma Stem-like cells through Suppression of EZH2-NOTCH1 Signaling Axis

Glioblastoma stem-like cells (GSCs) play essential roles in glioma growth, radio- and chemo-resistance, and recurrence. Elimination of GSCs has therefore become a key strategy and challenge in glioblastoma therapy. Here, we show that melatonin, an indolamine derived from I-tryptophan, significantly...

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Detalles Bibliográficos
Autores principales: Zheng, Xiangrong, Pang, Bo, Gu, Guangyan, Gao, Taihong, Zhang, Rui, Pang, Qi, Liu, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5332878/
https://www.ncbi.nlm.nih.gov/pubmed/28255276
http://dx.doi.org/10.7150/ijbs.16818

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5332878/
https://www.ncbi.nlm.nih.gov/pubmed/28255276
http://dx.doi.org/10.7150/ijbs.16818

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