An Exploratory Study to Determine Whether BRCA1 and BRCA2 Mutation Carriers Have Higher Risk of Cardiac Toxicity

Anthracycline-based cardiotoxicity is concerning for women with breast cancer and portends a dose-dependent risk of developing left ventricular dysfunction. Overall, the prevalence of heart failure (HF) is ≈2% of the total US population; however, BRCA-deficient mice have shown increased HF. We evalu...

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Detalles Bibliográficos
Autores principales: Sajjad, Monique, Fradley, Michael, Sun, Weihong, Kim, Jongphil, Zhao, Xiuhua, Pal, Tuya, Ismail-Khan, Roohi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333048/
https://www.ncbi.nlm.nih.gov/pubmed/28157161
http://dx.doi.org/10.3390/genes8020059

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333048/
https://www.ncbi.nlm.nih.gov/pubmed/28157161
http://dx.doi.org/10.3390/genes8020059

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