Elaborated Action of the Human Primosome

The human primosome is a 340-kilodalton complex of primase (DNA-dependent RNA polymerase) and DNA polymerase α, which initiates genome replication by synthesizing chimeric RNA-DNA primers for DNA polymerases δ and ε. Accumulated biochemical and structural data reveal the complex mechanism of concert...

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Detalles Bibliográficos
Autores principales: Baranovskiy, Andrey G., Tahirov, Tahir H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333051/
https://www.ncbi.nlm.nih.gov/pubmed/28208743
http://dx.doi.org/10.3390/genes8020062

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333051/
https://www.ncbi.nlm.nih.gov/pubmed/28208743
http://dx.doi.org/10.3390/genes8020062

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